Sunitinib Malate Capsule
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Pharmaceutical form Capsule
Category Anti Cancer
Brand Name Sunitinib Malate
Content Sunitinib (25mg)
Therapeutic Use Kidney cancer & Gastrointestinal stromal tumour
What is Sunitinib Malate Capsule?
- Sunitinib Malate Capsule is a drug that is used to cure gastrointestinal stromal tumours (tumours that grow in the stomach, intestine, or oesophagus) in persons who have had tumours that have not responded to imatinib or who are unable to take imatinib.
- Advanced renal cell carcinoma is also treated with sunitinib (a type of cancer that begins in the cells of the kidneys). It is used to help prevent the recurrence of RCC in persons who have had a kidney removed and have RCC that has not spread.
- It is also used in the treatment of pancreatic neuroendocrine tumours (tumours that start in certain cells of the pancreas).
- Sunitinib belongs to the kinase inhibitor class of drugs. It works by preventing the aberrant protein from causing cancer cells to grow. This may help decrease tumours by halting or slowing the spread of cancer cells.
How to Use It
- Sunitinib is available as a capsule that can be taken with or without food. It is normally given once a day for 4 weeks (28 days) in the treatment of gastrointestinal stromal tumours (GIST) or renal cell carcinoma (RCC), followed by a 2-week break before starting the next dose cycle and continued every 6 weeks for as long as your doctor prescribes.
- Sunitinib Malate Capsule is commonly used once a day for four weeks to prevent RCC (28 days) after which there will be a 2-week rest before starting the next dose cycle, which will be repeated every 6 weeks for a total of 9 cycles. Sunitinib is commonly administered once a day to treat pancreatic neuroendocrine tumours (pNET).
- It should be taken at the same time each day. Do not break, chew, or crush the capsules; they must be swallowed whole. Do not attempt to open the capsules.
- During your treatment, your doctor may slowly increase or reduce your Sunitinib Malate Capsule dose. This is dependent on how well the drug works for you and whether or not you have any negative effects. Even if you feel healthy, keep taking Sunitinib Malate Capsule.
Sunitinib Malate Capsule - PrecautionsBefore taking sunitinib,
- Inform your doctor If you are allergic to sunitinib, or any of the components in sunitinib malate capsules.
- Tell your doctor about any prescription and over-the-counter drugs, vitamins, and nutraceuticals you're taking or planning to take. Make a point of mentioning one or more of the following; antifungals like itraconazole, ketoconazole, and HIV/AIDS medications like atazanavir, indinavir, nelfinavir, ritonavir, and saquinavir; If you are receiving alendronate, etidronate, risedronate, or zoledronic acid injection, notify your doctor. Your doctor may need to adjust your prescription dosages.
- If you have or have ever had a bleeding problem, a blood clot in your lungs, or a slow, rapid, or irregular heartbeat, notify your doctor.
- If you are pregnant, expect to become pregnant, or plan to father a child, notify your doctor. While using Sunitinib Malate Capsule, neither you nor your partner should become pregnant. Sunitinib has been linked to a reduction in male and female fertility. Sunitinib has the potential to harm the foetus.
- If you're breastfeeding, let your doctor know. During your sunitinib treatment and for 4 weeks following your last dose, you should not breastfeed.
- Tell your doctor if you're taking sunitinib if you're having surgery. Because sunitinib can impact wound healing.
- It's important to understand that Sunitinib Malate Capsule can affect your skin to turn yellow and your hair to pale and lose colour. This is most likely due to the medication's yellow coloration.
- You should be aware that sunitinib might induce osteonecrosis of the jaw, particularly if you have dental surgery or therapy while taking it. Before you start taking sunitinib, a dentist should check your teeth and conduct any necessary procedures, such as cleaning or repairing ill-fitting dentures.
How It WorksSunitinib Malate Capsule is a cancer-fighting drug. It acts by attaching to and inhibiting a specific cell surface protein (tyrosine kinase) that promotes cancer growth. It also prevents the tumour from forming new blood vessels. This is how it keeps dangerous tumours from spreading.
Side Effects - Sunitinib Malate Capsule
- Nausea, vomiting, diarrhoea, a change in taste, a decrease in appetite, watering eyes, puffiness around the eyes, numbness/tingling of the arms/legs, or weariness are all possible side effects. Most of these effects can be mitigated by eating numerous small meals or restricting activity.
- Remember that your doctor provided this medication because he or she believes the advantage to you exceeds the risk of adverse effects. The majority of people who take this medicine do not have any substantial adverse effects.
- If you experience any of the following serious side effects such as headache, rash/blisters on the palms of your hands, pain in the tongue/mouth, easy bruising, cold/heat intolerance, black/bloody stools, vomit that appears like coffee grounds, slow wound healing, pain in heart, symptoms of low blood sugar, contact your doctor right away.
- This drug has the potential to elevate your blood pressure. Regularly monitor your blood pressure and notify your doctor if the readings are too high.
- Due to the quick killing of cancer cells, Sunitinib Malate Capsule might induce negative effects. Your doctor may prescribe medicine and advise you to drink plenty of water to reduce your risk.
- This medicine has the potential to reduce the body's resistance to infection. If you acquire any signs of infection, such as a persistent sore throat, fever, or chills, call your doctor right immediately.
- Contact your doctor if you have any other side effects not listed above.
Some Tips for Sunitinib Malate Capsule
- Sunitinib is used to treat thyroid cancer.
- Consume it with or without food, and at the same time every day if possible.
- Diarrhoea is a possible side effect. Drink plenty of water.
- Prevent pregnancy while taking this prescription and for a month after you complete using it by using a reliable contraceptive technique.
- It may have an impact on the time it takes for a wound to heal.
- While using this drug, keep a close eye on your blood pressure. If you experience symptoms of very high blood pressure, such as severe headaches, confusion, vision problems, nausea, or vomiting, contact your doctor.
- Thyroid gland function must be monitored while using this medication. If you have weight gain, dry skins, or hair, tell your doctor.
- It has the potential to cause major bleeding problems. If you experience headaches, stomach pain, or see blood in your urine or stools, contact your doctor.
- If you are pregnant, expecting to become pregnant, or breastfeeding, do not use this medication.
Sunitinib Malate Capsule SupplierHealthiza is one of the leading Sunitinib Malate Capsule supplier and manufacturer, offering the best quality medicine globally through a validated cold chain secure shipment process. We use this process to manufacture, store and deliver medicines at a very specific temperature. Customers can avail of this premium quality pharma product at an affordable price from us.
Information for the patient
Read the package leaflet for indications, contraindications, side effects, dosage as well as information on the use of this product, or consult your doctor or pharmacist before use. Misusing medicines may be dangerous to your life or health.